PTSW-0

PTSW-0 suppository dissolution test cell for drug release testing from hydrophobic carrier preparations

Home   /   Galenic Instruments   /   Suppository Testing   /   PTSW-0

PTSW-0

PTSW-0 suppository dissolution test cell for drug release testing from hydrophobic carrier preparations

The PTSW-0 Suppository Dissolution Test Cell (Rotating Dialysis Cell) is placed into a normal USP type dissolution vessel placed into a dissolution bath to test the rate of dissolved active of suppositories and lipophilic carriers.

PTSW-0 Suppository Dissolution Tester


Construction
The cell is emerged in the dissolution vessel. It is developed for the study of drug release from hydrophobic carrier preparations, such as suppositories. It encloses a small volume (max. 30ml) of inner fluid by means of a dialysis membrane. The cell itself rotates horizontally in a larger volume of test media which has the same pH as the inner volume. The sample is inside the inner cell. The rotating speed is reduced in a rotation of 2:1. The active dissolves through the membrane into the outer phase and can be measured therein using common technology like UV/VIS. It is proved that the cell is a suitable tool to study factors which may influence the dissolution and absorption of controlled release formulations.

Cell Design

  • Drive shaft
  • Reduction gear drive
  • USP glass vessel
  • Thermometer
  • Agitator blade
  • Dialysis membrane
  • O-ring
  • Dialysis cell
  • Plastic insert supporting membrane
The PTSW O can be used inside the Dissolution Bath types PTWS120D/S, PTWS 300/310, PTWS 600/610, PTWS 820D and 1200/1210/1220.



Features
  • Variable rotation speed, using reduction gear
  • Use it in every PTWS


Advantages
  • Can be used in a common dissolution bath having a suitable drive system (drive shaft design made to fit into PTAG Dissolution Baths only)
  • Easy to operate and set-up

Technical Specifications

Parameter Specification
Cell rotation speed 5 - 60 rpm
Drive gear Speed reduction ratio 2.1
Filter membrane Typical: Millipore Durapor HPVL 0.45 µm

We reserve the right to make technical changes without any prior notice.



Included in the Standard Supply Scope
  • Complete PTSW-0 Suppository Dissolution Test Cell (part. no. 39-00502)

Downloads
Brochure PTSW-0



Request for Quotation
      REQUEST A QUOTE

Pharma Test Instruments India Private Limited
Pragathi Nagar, Medchal Dist. Hyderabad - 500090, Telangana. T: +91 40 48591800 E: c.neelam@pharma-test.in




MEMBER OF THE PHARMA TEST GROUP