The compact, 8 station tablet dissolution testing instrument.
The PTWS 820D is an 8 position, single drive compact tablet dissolution testing instrument for solid dosage forms as described in USP chapter [711/724] and EP section [2.9.3/4] as well as the DAB and Japanese Pharmacopeia section [15].
PTWS 820D is an 8 position dissolution bath controlled by a color touch screen
User Interface
In keeping with our cutting edge design, a large color, touch screen allows control of the various mechanical features of the instrument such as the tool stirring speed, lift drive and heater. The instrument control is menu driven using a resistive touch screen and selection wheel technology. Visual signals on the display inform the user of the status of critical instrument parameters, e.g. bath target temperature not reached. Access to the instrument can be password controlled if required. If certain operational parameters form a regular feature of the daily routine, then these can be incorporated into a test method for faster set up.
These parameters can be tool speed, target bath temperature, sampling time points and so on. The test method memory capacity is almost limitless. As soon as the test is started, a screen saver can be activated with the most important information displayed in large script so that this information remains visible even at time when the operator is not standing directly in front of the instrument.
User Interface
Stirring Tools
The PTWS 820D uses the Pharma Test MonoShaft™ design. The tools consist of the main shaft plus interchangeable tool heads (adapters). The main shaft remains in place in the instrument regardless of the tool head being used. The clearance of each tool from the vessel base will always be correct once the main tool shaft has been installed and qualified with any one of the tool sets once. Each stirrer can be raised by hand into a convenient position for easy vessel removal or insertion. PTWS 820D is capable to perform a staggered start for each of the eight positions
Vessel Centering System
The PTWS 820D features a rigid and precise three-point individual centering system for each dissolution vessel (picture shows view from below). The vessels are held in position by three adjustable noses and are inserted into the instrument support framework.
The access points for sampling as well as the openings for the tools are contained in an auxiliary, low evaporation, vessel cover. Each USP Borosilicate glass vessel has a batch code on top of the flange for easy visibility and positioned placement inside the water bath cover.
Lift Mechanism
The upper drive is motorized and electronically controlled. It offers eight programmable positions: an upper cleaning and instrument qualification position and lower working positions are programmable depending on the type of stirring tool used. The upper position offers ideal access to the stirring tools and vessels for a change of tools and cleaning steps between the dissolution tests.
The electronically driven lift mechanism is located centrally above the water bath. This ensures that the whole lift drive mechanism is positioned in a way so that the tool shafts are always kept parallel and at a 90˚ angle to the vessel walls when in the working position.
| Parameter | Specification |
| Display | 6", 320X240 pixel color LCD, illuminated |
| Data Entry | Resistive touch screen |
| Acoustic Signal | Acoustic signal for operator information at programmable intervals |
| Timer | Programmable sampling times, wake-up and sleeping mode, operation time information and timer count-down mode |
| Stirrer Position | 8 programmable stirrer immersion positions (paddle over disk, transdermal cylinder etc.) |
| Testing Method Descriptions | Unlimited number of different test descriptions can be stored on SD card |
| User Access Control | Multiple level access control |
| OQ, PQ control | Programmable time periods to remind on QO or PQ testing |
| Printer | External PT-RP80 report printer |
| Number of Stirred Vessels | 8 (4 by 2 or 2 by 4 arrangement) |
| Standard Vessels | 1 liter USP/EP Borosilicate glass vessel, each individually coded |
| Speed Control | 25 - 250 RPM |
| Speed Accuracy | ۬% of set speed, typically < 1% |
| Stirrer Shaft Wobble | Better than 0.2 mm total run out |
| System Tools | MonoShaft™ stirrer design, USP/EP apparatus 1, 2, 5, 6 tool adapter, cream cell, transdermal patch tools, each tool and vessel individually coded |
| Heating System | Pump for water circulation and 1400W heater for fast heating up |
| Heater Range | 25 - 45˚C |
| Heater Accuracy | ± 0.2˚C inside the water bath |
| Heat Up Process | Energy saving, programmable "wake up" heater function and "sleep mode" |
| Water Circulation | Water circulated from external heating system through special diffuser inside the water bath |
| Vibration Elimination | External heating system, spring loaded pump assembly |
| Calibration | Built-in calibration procedures for speed, temperature control, OQ/PQ interval programmable including alarm indicator |
| Bench Space Requirement | 45 X 75 cm (2 by 4) or 75 X 45 cm (4 by 2) |
| Packaging Dimensions | |
| Certification | All components certified to USP / EP requirements |
| CE / EMC Certification | All CE / EMC Certification provided |
We reserve the right to make technical changes without any prior notice.
PT-RP80 Report Printer
Use the PT-RP80 serial report printer to print out the runtime report of the PTWS 120S.
